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Circulating MOTS-c declines with age and tracks with insulin resistance, making it both a potential longevity biomarker and a therapeutic target

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Synthetic Lipolytic Domain Characterization Ng et al., Hormone Research (2000) Ng and colleagues conducted foundational characterization studies of the AOD-9604 synthetic lipolytic domain using a combination of in vitro adipocyte assays and in vivo obese Zucker rat models