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Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition[J] J

In the system of Ad-P450 cells, it inhibits five P450 enzymes in a concentration-dependent manner (Sasaki et al., 2017)
For type 2 diabetes with obesity: CagriSema provides dual benefit superior weight loss plus enhanced glycemic control through complementary mechanisms

These miRNAs showed promising diagnostic accuracy, especially miR-574-3p and miR-200a-3p, based on ROC curve analysis [332]

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