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Potential side effects include: Nausea or mild stomach upset Fatigue Headache Gas or changes in bowel movements Low blood sugar (rare) If side effects are prolonged or difficult to tolerate, providers may recommend alternatives such as tirzepatide, which can have a different side effect profile.

Shimazu, T

When children remain refractory to acute or prophylactic treatment, or the episode differs from previous ones, the clinician should consider the possibility of an underlying disease and further mono- or combination therapy and psychotherapy can be guided by accompanying comorbidities and specific sub-phenotype

We used SAIGE 46 to obtain single-variant summary statistics, adjusting linear regressions for age, sex, and the first ten genetic principal components