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But even considering that EC50s obtained by the transient methods were determined to be 16-fold less sensitive than in measurement-quality stable cell lines, no OH-P mutant was sufficient to pursue further

These results suggest that NRF2 serves as a biomarker for predicting ferroptosis by targeting LDHB and SLC7A11 in KRAS -dependent cancer cells, consistent with previous finding that LDHB plays a unique role in KRAS-mutant lung cancer [27, 56]

Importantly, GGT and insulin resistance were closely correlated [Figure 2]

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