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[102] investigated the anti-inflammatory activities of ALA on cervical inflammation and shortening after primary tocolysis through a pilot, randomized, placebo-controlled study

Although superoxide anion and hydrogen peroxide are not particularly reactive they may synergize with specific factors, eg iron, generating potent free radicals such as hydroxyl radical, which may cause direct injury through alteration of vital cellular macromolecules (DNA, protein or lipids)

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By stimulating Nrf2 in microglia, SF increased antioxidative capacity, phagocytosis, and hematoma resolution [254,257]