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The other two cysteine GPx monomeric isozymes, such as GPx7 and GPx8, are expressed exclusively in the lumen of the endoplasmic reticulum (ER)

Nature 392 , 821824

doi: 10.3389/fmed.2026.1810363 Received 13 February 2026 Revised 18 March 2026 Accepted 23 March 2026 Published 04 May 2026 Volume 13 - 2026 Edited by Ramona Cioboata, University of Medicine and Pharmacy of Craiova, Romania Reviewed by Robert Steven Wallis, The Aurum Institute, South Africa Giuseppe Castaldo, University of Naples Federico II, Italy Updates Copyright 2026 Barne, Shevade, Bhattacharyya, Christopher, Nair, Abhyankar, Halder, Vora, Khanna, Swarnakar, Chhajed, Santhalingam, Nair and Salvi

Understanding the mechanisms behind these responses can help researchers interpret observations more confidently

The mode of action of electromagnetic fields may affect calcium ion flux through changes in membrane potential, conformational changes in membrane proteins, or mitochondrial functional regulation