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We demonstrated for the first time that oxidative stress induced a significant loss of mitochondrial mass by decreasing mitochondrial number and volume density in the ONH astrocytes

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By reducing oxidative stress in the brain, vitamin C and glutathione may help protect against neurodegenerative conditions and support overall cognitive function

J Gerontol Ser A 75:20812088 Wang D, Yang Y, Zou X et al (2020b) Curcumin ameliorates CKD-induced mitochondrial dysfunction and oxidative stress through inhibiting GSK-3 activity

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