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Evidence for bodybuilding-specific outcomes, such as lean mass gain or fat loss in healthy, non-HIV populations, is comparatively thin and largely extrapolated rather than directly studied in controlled trials

Excessive caffeine consumption may interfere with iron absorption and stress the adrenal glands, potentially accelerating hair loss in susceptible individuals

Combining compounds multiplies the number of potential side effects at play, and stacking unapproved research chemicals without medical supervision carries meaningfully more risk than using a single compound on its own

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