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The study was based on an analysis of medical records in Scotland

Neurological manifestations are particularly concerning and may include peripheral neuropathy with paresthesias (tingling and numbness in hands and feet), ataxia, impaired proprioception and vibratory sense, cognitive impairment, memory loss, and in severe cases, subacute combined degeneration of the spinal cord

These findings establish PKA as a critical regulator of LD lipolysis via HSL activation, directly connecting this pathway to the superior efferocytic capacity of M2 macrophages

Jiyan Yuan and Zeliang Wei contributed equally to this work

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