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Clin Rev Allergy Immunol 42(1):7178

62 However, when the animals are pretreated with ferrous iron, not only is the nitration pathway enhanced, but LPO suddenly becomes a relevant part of the pathomechanism

The brain substantia nigra in PD has a high level of expression of the VD metabolizing enzyme and 1 hydroxylase, and VD can stimulate the expression of tyrosine hydroxylase, a key enzyme of dopamine synthesis in PD, which affects the production and turnover of dopamine, therefore, the role of VD in the development process of PD has received increasing attention (85, 86)

FIGURE 1 2.3 Fetal sex determination and molecular analysis We isolated genomic DNA from the fetal tail using the HotSHOT method (Truett et al., 2000) and determined fetal sex using a PCR-based assay previously described (Thomas et al., 2021)

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