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Excessive ROS production leads to serious damage to organelles and DNA, or induces programmed cell death (e.g., ferroptosis)
Thus, the debate about the role and effectiveness of supplements/drugs containing l-Cys is still open
Cellular investigations reveal further nuances
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SKN-1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for lifespan extension in Caenorhabditis elegans
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