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The potential of CD38-targeting sdAbs has been explored through the creation of different structures, such as chimeric antibodies, biparatopic antibodies, heavy chain-only antibodies, and half-life-extended nano-BiKEs, which show promise for the treatment of MM

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A pharmacokinetic study conducted in healthy volunteers and patients with mild, moderate, and severe renal impairment (n=24, 6 subjects in each group) receiving single dose desmopressin acetate (2 mcg) injection demonstrated a difference in desmopressin acetate terminal half-life