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The Unfolded Protein Response Regulates Hepatic Autophagy by sXBP1-Mediated Activation of TFEB

The high local potency combined with short half-life offers theoretical advantages over systemic analogs: targeted effects with reduced whole-body exposure and associated risks

irritability, anxiety, dysphoria)(Gupta et al, 2023)
, 2007), preventing the production of adenosine triphosphate (Bolaos et al

Intra-articular injection of RIPK3 or MLKL inhibitors has been demonstrated to significantly prevent cartilage degeneration and synovial inflammation, revealing potential therapeutic targets for temporomandibular joint osteoarthritis (He et al., 2022)
