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H.DavenportA

Preventing the oxidation (darkening) of existing skin melanin* 2

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There was evidence that mice without efficient expression of SOD2 enzyme resulted in significant epidermal thinning. In humans mitochondrial dysfunction promotes cellular senescence in epidermal keratinocytes in culture. [7] This means because of senescence, there were fewer cells in the epidermis, causing it to be thinner

References Altamura S, Muckenthaler MU (2009) Iron toxicity in diseases of aging: Alzheimers disease, Parkinsons disease and atherosclerosis
