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Efficacy studies: Sndergrd et al

Low vitamin B12 has recently been linked to chronic migraine, and high homocysteine, with low cofactors and alterations in MTHFR (remember, the one that allowed the passage of THF to M-THF), has been linked to migraine with aura, due to incorrect methionine synthesis, which ultimately leads to an increase in homocysteine, causing an increase in reactive oxygen species (causing oxidative stress)

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Klomparens E.A., Ding Y

Among prediabetic participants, 87.7% reverted to normoglycemia with the combination, compared with 32.2% on placebo

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