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Efficacy and Safety of Recently Approved Drugs for Sickle Cell Disease: A Review of Clinical Trials

doi: 10.3389/fmicb.2022.846336 386 ZhouL.ZhangJ.YanM.TangS.WangX.QinJ

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These chelators cannot use together with reducing reagents such as DTT (dithiothreitol), -me ( -Mercaptoethanol), and TCEP (TRIS (2-carboxyethyl) phosphine) since the reducing reagents can strip off the metal from these resins, resulting in the rapid loss of the protein binding capacity