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To investigate the mechanism of this regulatory control, the authors performed single-cell RNA sequencing of the ILC3 cells and noted the expression of VPAC 2 , one of the receptors for VIP in these cells, and they found that ILC3s in cryptopatches and isolated lymphoid follicles were in close association with VIP-immunoreactive nerves and the expression of VIP in submucosal neurons was regulated by feeding (616)

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