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Interestingly, this infection has also been connected to ankylosing spondylitis, an autoimmune condition that causes pain and fatigue

CCR8 is not essential for the development of inflammation in a mouse model of allergic airway disease

ANSWER: There are many reasons for reactions such as this

In glioblastoma, mitochondrial Nip3-like protein X (NIX), whose expression levels are increased by NRF2, promotes HIF elevation, resulting in the maintenance of glioblastoma stem cells 63

These outcomes perpetuate a vicious cycle of neuroinflammation, with gut microbiota emerging as a potential key driver (Zhou et al., 2022) have demonstrated that gut dysbiosis promotes neuroinflammation by activating inflammasome signaling pathways