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However, since factors other than glutathione contribute to acrolein resistance, the ALE strategy often yielded strains with reduced glutathione content (Nho et al., 2025)
Upon infection or invasion, enzymes break hCAP-18 down, releasing the active LL-37 peptide
Lipid metabolism Lipidomic studies have shown that phosphatidylethanolamines (PEs) with arachidonic acid (AA) or its derivative adrenergic acid (AdA) are the key phospholipids for oxidation, and their peroxidation is considered a significant driver of ferroptosis [19, 21]
doi: 10.3164/jcbn.11-74
doi: 10.3390/v10080392 144 KlokF
