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Gut microbiome-mediated mechanisms for reducing cholesterol levels: Implications for ameliorating cardiovascular disease

In: BerkemanLKawachiI, editors

A.MllerJ.LevineH

The researchers examined the impact of these interventions through a biochemical characterization of brain homogenates, quantifying oxidative and inflammatory markers such as lipid peroxides, glutathione (GSH), glutathione S-transferase (GST), 5-lipoxygenase (5-LOX), cyclooxygenase-2 (COX-2), leukotriene B4, prostaglandin E2, and ascorbic acid using spectrophotometric assays and ELISA

The complex relationship between modulation of RBC deformability by NO and oxidants, and their effects on viscosity and vascular shear stress should be investigated in more detail