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Description
Nasal delivery bypasses first-pass metabolism and allows direct transport to the systemic circulation and liver via the olfactory nerve, while rectal administration avoids gastric acid degradation and enhances local absorption in the colon

Yuvaraj P, Subramoniam A

10.1038/nm.3762 24 KoK.-M.LeonT

10.1155/2020/8683404 Oxid Med Cell Longev

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