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Description
They pass on the signal from the activated GPCRs to the cell interior and lead to a cascade of interactions and enzyme activities that ultimately brings about a change in cell function

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ALS ALS is a degenerative disease of the nervous system that gradually affects specific motor neurons in both the cortex and spinal cord, ultimately resulting in paralysis and fatality
Of note, FSP1 knockdown in cells resulted in blockage of the RAS-selective lethal 3 (RSL3)-induced expression of charged multivesicular protein (CHMP)5 and CHMP6 at the plasma membrane

ACS Biomater Sci Eng 2022;8(3):11151131
