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10 Many efforts have been made in response to each process of the drug transportation, which have also been accompanied by reviews of latest progress in this field, but most of literature emphasize the BBB breakdown in specific brain disorders, 11,12,13,14 or give a general review of delivery strategies concentrating on the barrier physiology

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With precise blunt dissection, the tendon fibers were removed from the muscles, taking care not to damage the tendon-bone insertion on the patella or the muscle-bone insertion on the proximal third of the femur