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Intracellular accumulation of ascorbic acid is inhibited by flavonoids via blocking of dehydroascorbic acid and ascorbic acid uptakes in HL-60, U937 and Jurkat cells

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Furthermore, a higher incidence of ALI with a direct pulmonary source may be associated with a higher frequency of ARDS and a higher mortality rate [18, 84], possibly due to poorer respiratory mechanics and lung elastance when compared to indirect insults [85]

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