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Description
Covalent inhibitors form a bond in the active site at Glu226

By inhibiting NNMT, 5-Amino-1MQ reduces 1-MNA formation and alleviates the methyl sink, increasing SAM availability for other methylation reactions, while freeing nicotinamide for recycling through NAMPT toward NAD

Intended Use: For in vitro laboratory research and educational purposes only

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