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Allergic Reactions (Rare): Although rare, some individuals can have an allergic reaction to the injection, ranging from a rash or itching to more severe symptoms like swelling of the face, tongue, or throat, dizziness, or difficulty breathing

Subsequent in-vitro work has examined its action on tendon-fibroblast outgrowth, gastrointestinal-tract protection, and angiogenesis pathways via VEGFR2/eNOS signaling

sustained growth-hormone-axis stimulation also carries a theoretical, class-wide concern for worsened insulin resistance, a recognized effect of excess growth hormone exposure generally Evidence snapshot: The strongest available evidence is a small 1997 randomized, placebo-controlled human trial (19 adults aged 55-71) testing a closely related GHRH(1-29) analog over 16 weeks, which found increased IGF-1 in both sexes, a significant lean-mass increase in men only, and increased skin thickness in both sexes

If nausea persists beyond 3-4 weeks on a stable dose, consider reducing to the previous dose level and attempting re-escalation more gradually after 4-6 weeks

Because every plan is custom, two people with similar goals may follow very different protocols