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Description
NRF2 promotes the expression of NADPH-generating enzymes, including the rate-limiting enzyme glucose-6-phosphate dehydrogenase (G6PD) in the pentose phosphate pathway (PPP)
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Ruthenium complexes as anticancer agents
For instance, in Farber disease, a fatal lysosomal storage disorder, mutations in the ASAH1 gene encoding acid ceramidase lead to ceramide accumulation
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