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Chemical & Structural Highlights

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Several observational studies using similar formulations and instillation protocols ranging from weekly to monthly to PRN and follow-up intervals of a few months to several years reported efficacy rates of 25 to 90%

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Activation of the Nuclear Factor Kappa B (NF-B) and COX 2 signaling pathways can also increase the concentration of pro-inflammatory cytokines and the activator cascade to activate other cytokines that induce inflammation (33)