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PNPLA1 is a transacylase essential for the generation of the skin barrier lipid - O -acylceramide

The role of insulin-like growth factor binding proteins in metabolic syndrome Recall that IGFBPs have a very important role, not only in modulating free IGF-1, half-life and localisation, but also by possessing IGF-independent activities mediated by their own receptors

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Laboratory investigations reveal that 5-amino-1MQ suppresses lipogenesis in adipocytes with an EC of 30 M, mechanistically achieved through restoration of cellular NAD+/SAM ratios that favor lipolysis over lipid storage

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