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The distinctions between the molecular mechanisms of mucin production and secretion within muco-obstructive lung diseases are discussed with a focus on several cytokines such as IL-1, secretagogues like ATP, and protein chaperones such as ERN2

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Acknowledgements Special thanks are due to Paola Murano from Nefrocenter Research Network, for her complimentary editorial assistance, and to Members of the AMD-OSDI Study Group on Injection Technique for critical reading and approval of the manuscript
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