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A key mediator of blood vessel function is nitric oxide (NO), a tiny gas molecule produced in the blood vessels, nerves, and immune cells.[12] Best known for its role in maintaining blood pressure, NO also mediates penile erections, supports healthy blood flow to the brain, enhances muscle oxygen use during exercise, and helps protect against infections

Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation

Physiol Behav