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Several review articles [11,81,82] discuss the causal relationship between an impairment of the homeostasis of redox-active metal ion and the irreversible transformation of biological constituents, such as proteins, lipids and the DNA strand, into oxidation products, and of the following biochemical impairment to the onset of a wide array of diseases

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A.BossJ.GodwinC.MukherjeeB.FeldmanE

While a mild rash around this area can be normal, it could also be a sign of a serious allergic reaction if it gets worse or doesnt go away