glutathione switch persister cells Ferroptosis Dependence in Drug-Tolerant Cells👇 ✓Chemotherapy or BH3 mimetics trigger mitochondrial outer membrane permeabilization (miMOMP) in a subset of cancer cells. Instead of undergoing full apoptosis, these survive the initial Plasticity, signaling, and metabolic rewiring

The perfusion process produced significantly lower BisAb aggregates compared to the fed-batch process

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We put forward the hypothesis of ferroptosis, a recently identified iron-dependent cell death, as a potential underlying mechanism of BD