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In HD, astrocytes undergo functional asthenia manifested in the deficient K + buffering and glutamate clearance

Appl Immunohistochem Mol Morphol (2020) 28:3608

However, KEAP1 regulates multiple pathways beyond NRF2 60,82 , and the contributions of NRF2 to lipid homeostasis have been reported to be pleiotropic and context-dependent 83
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