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Dietary choline is partially absorbed by intestinal cells or metabolized by gut bacteria ( Figure 1 )

However, therapeutic doses for treating deficiency range from high-dose oral supplements (1,0002,000 g daily) to intramuscular injections of 1 mg, particularly for pernicious anaemia or malabsorption conditions

[Google Scholar] 130.Woldhuis RR

This review examines the sources of oxidative stress in AKI, the mechanisms by which oxidative stress-induced ER stress contributes to cell death through autophagy and apoptosis, and discusses the potential of antioxidants to alleviate these processes in the treatment of AKI

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