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(PubMed) Jujic A, Molvin J, Schomburg L, et al
Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75
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The first step in the reaction is catalyzed by GCL, a heterodimer made up of a catalytic subunit (GCLC) that possesses the enzymes active site and performs the actual amino acid linkage, and a modulating subunit (GCLM) that regulates the activity of GCLC, as reviewed in Figure 1
