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Clinical Evidence for NR: Human trials demonstrate 40-60% increases in NAD+ levels at doses of 1000 mg daily Improved energy levels reported in participant surveys, though more research is needed to confirm long-term health benefits Safety profile appears favorable

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For mortality from influenza and pneumonia, the main effect of testosterone was not statistically significant (HR = 0.94 [0.77, 1.15]), but there were significant interactions between testosterone and the final two age splines (spline-2: HR = 1.62 [1.18, 2.24]

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