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Description
B.Mosquera-GiraldoL
The cofactors like selenium, zinc, copper of many enzymes may be replaced by lead, and thereby, resulting in enzyme inactivation
Journal of Clinical Oncology , 28 (16), p.2768
Agents targeting mutations in IDH1 mutations, such as AG-120 and FT-2102, and IDH2, such as AG-221 have shown promise in clinical trials, effectively lowering 2-HG levels, inducing cellular differentiation, and demonstrating clinical efficacy in patients with relapsed or refractory AML [23]
Food and Drug Administration, have hardly been studied in people and may not be intended for human use at all
