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Phentermine is a prescription appetite suppressant that temporarily aids weight loss by releasing norepinephrine (and to a lesser extent dopamine) in the brain, which reduces hunger and increases alertness

Specifically, it helps convert homocysteine to methionine and supports the conversion of methylmalonyl-CoA to succinyl-CoA a step in the metabolic pathway that generates cellular energy from fatty acids

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Despite its importance, B12 deficiency is remarkably common particularly among vegetarians, older adults, individuals with digestive conditions, and anyone whose body has difficulty absorbing this vitamin from food or oral supplements

Depression and cardiovascular disease: a clinical review