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Clinical trial design in ALS continues to advance, allowing for better measurement of changes in outcomes via patient stratification, identification of patients most likely to benefit from specific drug mechanisms, and methods for faster drug development and availability to patients

10.1164/rccm.202403-0636OC 64 LiC.LuY.DuS.LiS.ZhangY.LiuF.et al (2017a)