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Scientific reviews show a compelling mechanistic story supported almost entirely by animal data (Park, 2025)
Consequently, therapeutic concentrations in brain tumors remain suboptimal, undermining curcumins potential to modulate pathways like p53 and JAK/STAT in GBM [72, 73]
If pregnant, breastfeeding or planning to become pregnant, consult your physician before use
Pediatrics 69: 255259
Studies have observed decreased cyclooxygenase-2 (COX-2) gene expression, reduced myeloperoxidase activity, and lower levels of pro-inflammatory cytokines including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-)
