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The resulting p values were corrected for multiple hypothesis testing according to the Benjamini and Hochberg method 90

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Key pharmacokinetic parameters, including maximum concentration ( C max ), time to reach maximum concentration ( T max ), and area under the curve (AUC), were assessed to determine the absorption profile (Tables 2 and 3)

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To quickly identify compounds that increase NADPH levels in cells, we developed a high-throughput screening system based on iNap1 fluorescence and screened 1419 FDA-approved drugs