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Folate Insufficiency and Transport Abnormalities Despite the challenges for treating ASD, emerging data suggests that folate pathway abnormalities may play a role in the pathogenesis of ASD

90 Histone demethylase KDM3B is another potential epigenetic regulator of ferroptosis, as it upregulates the expression of SLC7A11, indicating that ferroptosis is influenced by epigenetic mechanisms

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The trial met its primary endpoint, demonstrating statistically significant and superior weight loss with CagriSema versus placebo
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