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MATERIALS AND METHODS Study Design This study was a single-site, double-blind study carried out at Leiden University Medical Center (LUMC) and is summarized in the Consolidated Standards of Reporting Trials (CONSORT) flow diagram (Figure 1)
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The deletion of the sirA- encoding ABC transporter resulted in the increased secretion of sirodesmin into the medium, indicating the SirA is not necessary for the production of sirodesmin
