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Description
Polyamines in cancer: integrating organismal metabolism and antitumour immunity
Hepatic synthesis of carnitine from protein-bound trimethyllysine
By converting fat into energy, supplemental l-carnitine allowed for sparing of amino acids thereby leading to protein accretion in the muscle of swine [51]
In addition to OMM substrates, several inner mitochondrial membrane (IMM) proteins, such as uncoupling proteins UCP2 and UCP3 70,71,72 , as well as SLC25A4 (identified in this study), are also polyubiquitinated and degraded via the proteasome
The work described below is aimed at addressing these outstanding questions to better understand brain bioenergetic changes that precede AD pathology
