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Description
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As was noted for DNMT1 and PRMT3, sigmoidal dose-response curves and reliable estimates of IC 50 values could not be obtained since no significant inhibition was observed at the tested NNMT inhibitor concentrations
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In fact, some research suggests AOD 9604 may have cartilage-supportive properties
The mechanism behind this regional selectivity may relate to differences in beta-3 adrenergic receptor density between visceral and subcutaneous fat depots
