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doi: 10.1073/pnas.1032913100

Synergistic Effect of Folate-Mediated Targeting and Verapamil-Mediated P-Gp Inhibition With Paclitaxel-Polymer Micelles to Overcome Multi-Drug Resistance

Golshani P, Hutnick L, Schweizer F, et al

Inhaled nano-based drug delivery systems have many advantages over conventional drug or micron delivery systems for the treatment of PF [93]: (1) Targeted drug delivery [94]: increases the concentration of drug in the lungs, controls the release of drug, overcomes the lung barrier, reduces the dose of drug thus reducing the side effects of treatment and improving patient compliance