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Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus

Work by Pickart and Campbell using genome-wide profiling revealed that GHK-Cu affects the expression of approximately 4,000 human genes resetting patterns associated with tissue damage and ageing toward profiles more characteristic of healthy tissue

In particular, PI3K/AKT stimulates expression of the glucose transporter 1 (GLUT1), hexokinase (HK-1), and phosphofructokinase (PFK-1)

The evidence base consists primarily of animal studies with limited human clinical data

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