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Considering the remaining obstacles in melasma treatment, a deeper comprehension of its multifactorial pathogenesis can improve therapeutic outcome and overcome its high recurrence and resistance rates (Rajanala et al., 2019b

10.1074/jbc.275.18.13727 157 Petaja-RepoU

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The results of these studies support and confirm observations in-vivo indicating that intact DSIP crosses the BBB by simple transmembrane diffusion
