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The peptide upregulates MMP-2 expression in dermal fibroblasts by 85%, facilitating breakdown of damaged collagen and enabling cellular migration through dense matrix environments, while simultaneously enhancing production of tissue inhibitors of metalloproteinases (TIMPs) to prevent excessive degradation

The peptide works particularly well for tendinopathies, ligament injuries, muscle strains, and gastrointestinal inflammation

In further embodiments, the invention encompasses use of one or more cations of the invention to treat tumorigenesis and metastasis of NNMT-positive cancers